Pc acting weirdly whenever a full screen application is open

[Windows 10]

Whenever I run a full screen application my pc just seems to break down. The keyboard is not registering inputs all the time, when I hold keys it seems to be registering as me repeatedly pressing them with various delays. Random keys are also being inputted despite me not pressing them. Same with the mouse. My pc also randomly turns off sometimes while I was in a middle of a game. If a fullscreen app isn't running either in the front or background, everything works fine, but whenever one does, this always happens.I tried to fix it in various ways, but nothing worked so far, here's what I tried

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