Is it safe to delete entires from Autoruns when it says "File not found"?

[Mr_TommyGun]

I was looking through Autoruns to disable a couple of things that don't really need to run at start up, and I noticed that quite a few of those entries had "File not found" and then the path next to it. Is it safe to delete those entries or will it mess up my PC? One of them was in C:\WINDOWS\SysWow64, which is why I wasn't sure because I know that location holds important files. Another that I checked on to see where it lead me opened the registry to what I assume was an entry that was no longer needed, however I did not delete it yet just in case, but again, it said "File not found", so if i

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