How do I align a very large monitor with smaller ones for smooth mouse transition?

[Dr. Brian Stewart]

I have a very large monitor with a limited screen resolution. I also have several other monitors connected that are smaller. The ones to the right are stacked and end up being the same height of the big one. I have the monitors positioned using the display settings the best that I can. The resolution is set on the highest, recommended setting. When I move the mouse from the two smaller monitors on the right to the large one on the left, there is a dead zone at the top and bottom because the large one only connects to the middle of where the right monitors meet. Is there a way to adjust t

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